Original Articles · Vol. 1 No. 2 (2010)

Correlation Between FNAC and Open Biopsy in Cervical Lymphadenopathy in Children

Cover
JPSB
Journal of
Paediatric Surgeons of Bangladesh
Published : July 2010
CONTENTSVolume 01Number 2July 2010
Editorial
‘Constipation in Children’ – Think Twice Before Starting Treatment
Md. Kabirul Islam
86
Review Articles
Vaccination in Pregnancy
Shamim Fatema Nargis, Md. Shahinur Rahman
158
Original Articles
Operative Outcome of Acute Extradural Haematoma, Operated at Different Time Interval and Review of International Guidelines
MM Ehsanul Haque, S Sultana, SU Ahamed, Md. Abdullah Alamgir
88
Single Stage Correction of Rectovestibular Fistula
Kaniz Hasina, Abdul Hanif, S. M. Shafiqul Alam, Shahin Reza, Nazrul Islam, A. K. M. Mizanur Rahman, S. M. Shamsul Huda, M.M. Masud Pervez, Susankar Kumar Mondal, Shahnoor Islam
99
Bronchogenic Cyst
Mirza Kamrul Zahid, Anwarul Anam Kibria, AKM Razzaque, Md. Shamsul Alam, Shahinur Rahman, Kazi Saiful Islam
106
Comparison Between One Stage Correction of Vestibular Fistula by Transfistula Anorectoplasty (TFARP) and Anterior Sagittal Anorectoplasty (ASARP)
Jaglul Gaffer Khan, Mohammad Kabirul Islam, M. A. Rahaman, Jamila Akter, Kaniz Hasina, Susankar Kumar Mondal, Md. Ansar Ali
111
Correlation Between FNAC and Open Biopsy in Cervical Lymphadenopathy in Children
Tahmina Hossain, Md. Ruhul Amin, MTH Siddiqui, Md. Ashraf Ul Huq, Md. Matiur Rahman
118
Lubrication of Meatus and Circumcision Site for Prevention of Post-circumcision Meatal Stenosis in Children Younger Than Two Years Old
Susankar Kumar Mondal, Kaniz Hasina, Md. Ashraf Ul Huq, Md. Ansar Ali, Md. Mahbub-Ul Alam, Muhammed Moinul Hoque, Jaglul Gaffer Khan, A K M Mizanur Rahman, Shahnoor Islam
127
Postnatal Management of Prenatal Obstructive Hydronephrosis
Mugahid Al-Hassan, Paddy Dewan, Padma Rao
132
Study of Voiding Obstruction in Physiological Phimosis
Shahnoor Islam, AKM Amirul Morshed, Shafiqul Hoque
137
To Manage Infantile Hypertrophic Pyloric Stenosis by "Double-Y Pyloromyotomy" is a better Surgical Approach
Md. Ansar Ali, Kaniz Hasina, Shahnoor Islam, Md. Ashraf Ul Huq, Md. Mahbub-Ul Alam, Susankar Kumar Mondal
143
Use of Betel Leaves in Pediatric Stoma Care
Md. Ashraf Ul Huq, A K M Mizanur Rahman, Tahmina Hossain
148
Laparoscopic Repair of Peptic Ulcer Perforation - Our Initial Experience
Md. Saiful Hoque, Gazi Mohammad Zakir Hossain, Nur Hossain Bhuiyan, Md. Rashedul Hasan, Mayin Uddin Mahmud, Alamgir Rashid Chowdhury
153
Case Reports
Bilateral Lumbar Hernia - a Rare Occurrence in Infant
Shahnoor Islam, AKM Amirul Morshed, Md. Ashraf Ul Huq, Md. Mahbub-Ul Alam, Susankar Kumar Mondal, Kaniz Hasina
162
Inflammatory Pseudotumour of Mesentery - A Case Report
Bilal Mirza, Afzal Sheikh
166
The Official Journal of the
ASSOCIATION OF PAEDIATRIC SURGEONS OF BANGLADESH (APSB)
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Authors

  • Tahmina HossainAssistant Professor, Dept. of Pediatric Surgery, Dhaka Medical College & Hospital
  • Md. Ruhul AminAssociate Professor, Dept. of Pediatric Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • MTH SiddiquiAssociate Professor, Dept. of Pediatric Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Md. Ashraf Ul HuqAssociate Professor, Dept. of Pediatric Surgery, Dhaka Medical College Hospital, Dhaka
  • Md. Matiur RahmanProfessor, Dept. of Pediatric Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka

Keywords

Abstract

Background: Head and Neck region of the body has a rich network of lymphatic channel and intervening nodes. Out of total approximately 800 lymph nodes in the body about 300 are scattered in organized fashion in the neck region which are affected by various regional and systemic diseases. The conventional method of excisional biopsy is used to diagnose etiological causes of lymphadenopathy. In comparison to open surgical biopsy, FNAC is a simple, reliable and acceptable tool for the etiological diagnosis of lymphadenopathies. FNAC was first practiced by Grieg and Gray for the diagnosis of trypanosome in lymphnode in 1904. Now a day it is widely practiced in United States, United Kingdom and many other countries. In Bangladesh, many studies on FNAC are carried out and the results are highly appreciable and reliable. Methods: A prospective study for a period of 24 months was carried out on 50 patients with enlarged cervical lymph nodes from July 2003 to June 2005. During the two years study period, 56 patients with cervical lymphadenopathies were selected for FNAC and open biopsy following certain inclusion and exclusion criteria, in the Department of Pediatric Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka. Patients with acute lymphadenitis and lymphadenopathy due to leukaemia were excluded. Six cases were deleted from the study as smears from those revealed inadequate material and hence only 50 cases were available for study in the present series. Clinical findings, FNAC and biopsy reports were available in all the cases and were correlated with each other. Result: On biopsy, 27 cases were diagnosed as tuberculous lymphadenopathies, 15 cases as lymphoma and 8 cases as reactive changes. On FNAC, there were 2 false positive and 5 false negative cases in case of tuberculosis; 2 false positive and 1 false negative cases in lymphoma; 4 false positive and 2 false negative cases in cases with reactive hyperplasia. Sensitivity of FNAC in comparison to histopathological findings was 92.6% in case of tuberculosis; 86.7% in case of lymphoma and 50% in case of nonspecific lymphadenitis. Specificity of FNAC in comparison to histological findings was 78.3% in case of tuberculosis; 94.2% in case of lymphoma and 95.3% in case of nonspecific lymphadenitis. Accuracy of FNAC in comparison to histopathological findings was 86% in case of tuberculosis; 94% in case of lymphoma and 88% in case of reactive changes. Conclusion: The present study indicates that, FNAC is a simple, reliable and acceptable procedure for various lesions of cervical lymph nodes. It can be repeated if necessary. It also concludes that FNAC helps to confirm the clinical impression without open biopsy. Open biopsy can be avoided in many benign and malignant lesions of cervical lymph nodes. Fine needle aspiration cytodiagnosis can eliminate the need of hospitalization and surgery.

Journal of Paediatric Surgeons of Bangladesh (2010) Vol. 1 (2): 118–126

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